|
KMID : 1007320080140030246
|
|
Journal of the Korean Society of Menopause
2008 Volume.14 No. 3 p.246 ~ p.249
|
|
|
Comparison of Histologic Results from Hysteroscopic Biopsy and Blinded Biopsy by Currettage in Women with Tamoxifen Therapy after Breast Cancer
|
|
Lee Dong-Ok
Choo Chang-Woo
Lee Jung-Yun
Moon Kyoung-Yong
Jung Yeou-Kyung
|
|
|
Abstract
|
|
|
Objectives: To evaluate the accuracy of curettage compared with hysteroscopic biopsy in women on tamoxifen after the diagnosis of breast cancer.
Methods: A prospective observational study conducted with forty one women with postmenopausal bleeding during tamoxifen therapy. Under anesthesia, dilatation and curettage was immediately followed by hysteroscopic biopsy and the pathologic reports were compared.
Results: By curettage, 24.4% of women showed insufficient tissue for diagnosis compared with 7.3% by hysteroscopic biopsy. In thirteen women (31.7%) endometrial polyp was diagnosed by hysteroscopic biopsy, although all of them showed normal or atrophic endometirum only by curettage.
Conclusion: Hysteroscopic biopsy should be used for the evaluation of endometrial pathology in women on tamoxifen after breast cancer.
|
|
|
KEYWORD
|
|
|
Tamoxifen, Breast cancer, Endometrial evaluation, Hysteroscopy, Curettage
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|